Sabres vs. Predators all-time
| Buffalo Sabres vs. Nashville Predators all-time |
| 1990's | 3 | 1-2-0 | 0-2-0 | 1-0-0 |
| 2000's | 10 | 5-4-1 | 1-2-1 | 4-2-0 |
| 2010's | 8 | 2-4-2 | 0-2-2 | 2-2-0 |
| Overall | 21 | 8-10-3 | 1-6-3 | 7-4-0 |
| Series wins: | ||||
| Conference: | Western |
| Division: | Central |
| Founded: | 1998 |
| General manager: | David Poile |
| Head coach: | Peter Laviolette |
| Captain: | Shea Weber |
| Stanley Cups: | 0 |
| Presidents' trophies: | 0 |
| Minor league affiliates: | Milwaukee Admirals (AHL) Cincinnati Cylcones (ECHL) |
| Nashville Predators logos: | ||||
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| 1998/99 – 2010/11 | 2011/12 – present | |||
| Other Information: | ||||
| Mascot: Gnash | Arena: Bridgestone Arena | |||
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| Regular season meetings: |
| 12/5/1998 | A |  | W 3-1 |
| 1/28/1999 | H |  | L 4-2 |
| 10/20/1999 | H | | L 4-3 |
| 2/10/2000 | A | | W 2-1 (OT) |
| 1/6/2001 | A | | W 2-0 |
| 10/16/2001 | H | --- | T 3-3 |
| 11/13/2001 | A | | L 4-1 |
| 1/27/2003 | H | | L 5-1 |
| 11/29/2003 | A | | L 4-1 |
| 12/21/2006 | A | | W 7-2 |
| 2/27/2008 | H |  | W 8-4 |
| 12/1/2008 | H | | L 2-0 |
| 10/10/2009 | A | | W 1-0 |
| 3/20/2011 | H | | L 4-3 (OT) |
| 12/3/2011 | A |  | W 3-2 |
| 3/11/2014 | H | | L 4-1 |
| 3/27/2014 | A | | L 6-1 |
| 2/22/2015 | H | | L 2-1 (SO) |
| 3/21/2015 | A | | L 3-0 |
| 11/25/2015 | H | | L 3-2 |
| 11/28/2015 | A | | W 4-1 |
| 1/24/2017 | A | ||
| 2/28/2017 | H |